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Real members of MyMSTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

I have PPMS diagnosed 5years ago, And presently taking mounjaro 7.5 mg injections, What are the benefits of this versus ozempic?

A MyMSTeam Member asked a question 💭
Point Lookout, NY
December 22, 2025
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Ozempic and Multiple Sclerosis: Insights From Dr. Aaron Boster on GLP-1 Agonists Read Article...
A MyMSTeam Member

Hi I'm a pharmacy technician and GLP-1's (Mounjaro and Ozempic) are usually used to decrease insulin resistance. And insulins job in your body is to regulate how carbohydrates are processed for energy. So while GLP-1's are not used for the treatment of MS, I'm assuming you were prescribed them to help with the overall fatigue which could then help with muscle function by allowing you to move around.

Again, I'm not a doctor in the slightest or YOUR doctor either. This is just my best educated guess.

I'd recommend downloading your hospital's patient access app so you can shoot questions like this your provider directly. It makes it a lot easier to ask the source before letting forum's chime in (No hate either, that was just a statement from lived experience)

December 27, 2025
A MyMSTeam Member

My husband uses Ozempic but he doesn't have MS, he uses it for diabetes.

December 22, 2025
MyMSTeam

What are the benefits of Mounjaro versus Ozempic for someone with PPMS?

Unfortunately, the available information doesn't address Mounjaro or Ozempic in relation to PPMS treatment. These medications aren't typically used to treat multiple sclerosis itself.

For PPMS specifically, the only FDA-approved disease-modifying therapy Show Full Answer

What are the benefits of Mounjaro versus Ozempic for someone with PPMS?

Unfortunately, the available information doesn't address Mounjaro or Ozempic in relation to PPMS treatment. These medications aren't typically used to treat multiple sclerosis itself.

For PPMS specifically, the only FDA-approved disease-modifying therapy is ocrelizumab (Ocrevus). This medication works by reducing B cells, which are immune cells that contribute to MS by attacking the central nervous system. In clinical trials, ocrelizumab has been shown to slow disability progression in people with PPMS and delay the need for a wheelchair by an average of seven years.

If you're taking Mounjaro or considering Ozempic for a comorbid condition (like diabetes or weight management), it would be best to discuss the specific benefits and risks with your healthcare provider, as they can evaluate how these medications might interact with your MS treatment plan and overall health needs.

Other treatments for PPMS focus on managing symptoms like pain, fatigue, bladder control, and depression, along with physical therapy and lifestyle modifications.

December 22, 2025

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