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Real members of MyMSTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
March 6
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A MyMSTeam Member

I stopped my MS meds in 2005. They attacked my kidneys and now have chronic kidney disease. Stopping the MS meds is not likely to be the only cause of him being upset and mean. Most MS patients suffer from various degrees of depression and anxiety. For myself I began using Wellbutrin shortly after stopping MS meds. My neurologist has at times added antidepressants too. It was finding the right amount and type to help me. Even now I get angry at times and my wife feels it is about her even though it is all in me…

March 6
MyMSTeam

Is your husband's fever and mood related to stopping MS medication?

It sounds like you're dealing with a really tough situation. When someone stops their MS medication, symptoms can worsen or return, and fever can make MS symptoms significantly worse. Even low-grade fevers (like 98.9°F) can cause fatigue, vision problems Show Full Answer

Is your husband's fever and mood related to stopping MS medication?

It sounds like you're dealing with a really tough situation. When someone stops their MS medication, symptoms can worsen or return, and fever can make MS symptoms significantly worse. Even low-grade fevers (like 98.9°F) can cause fatigue, vision problems, and other symptoms to flare up because heat makes it harder for damaged nerves to send signals properly.

The combination of being off medication and running a fever could be intensifying his symptoms and affecting his mood and behavior. A MyMSTeam member shared experiencing "random low-grade fevers that make my MS symptoms worse," with another noting they feel "wiped out" with vision issues even from very mild temperature increases. What you can do:

First, it's important to contact his neurologist right away about him being off his medication and having a fever. They need to know both of these things.

For managing the fever at home:
- Monitor his temperature with a thermometer
- Ask his doctor about over-the-counter fever reducers
- Keep him cool and hydrated

About the screaming and tension:

Caregiver stress and frustration are real risk factors for relationship strain. When partners become caregivers, it can blur boundaries and create tension. Many couples experience this shift, and it's often worse when communication breaks down.

You both deserve support. Consider asking his doctor about:
- Resources for caregivers
- Whether mood changes could be MS-related
- Counseling for both of you

You're not alone in feeling this way, and reaching out for help is important for both of you.

March 6
A MyMSTeam Member

I agree that being off his MS meds isn't what is causing him to get angry and mean. Fear of the unknown and anxiety could play a part. This may sound (I can't think of the word) but seeing my husband deal with the diseases he has, maybe your husband is also reacting because he feels he needs to be the provider and protector and he doesn't feel like he is doing either very well. Talking, both of you, to his neurologist may help.

March 6
A MyMSTeam Member

Thank You for answering my question 🤗

March 7
A MyMSTeam Member

Maybe he is in partial denial? I had explosive issues not being able to do what I use to and the pressure in my head was overwhelming! I wonder especially since he's a man (no offense gentlemen); men want to be the caregiver, the one you lean on , the solid man of the house. I can imagine this causes a lot of depression and frustration. He does need to be on medicine to hopefully prevent getting worse (you can't take away the lesions once developed) I will be praying for you both to be able to get through this💕 🙏

March 6

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