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Real members of MyMSTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyMSTeam Member asked a question 💭
Westfield, MA

Ppms. Age 62

April 6
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Can gabapentin help with PPMS symptoms, and how long do side effects last?

Gabapentin can help manage certain PPMS symptoms, particularly those related to nerve damage. It's often prescribed off-label to treat:

* Muscle spasms and spasticity (muscle stiffness and pain)
* Nerve pain
* Numbness, pins and needles, or burning Show Full Answer

Can gabapentin help with PPMS symptoms, and how long do side effects last?

Gabapentin can help manage certain PPMS symptoms, particularly those related to nerve damage. It's often prescribed off-label to treat:

* Muscle spasms and spasticity (muscle stiffness and pain)
* Nerve pain
* Numbness, pins and needles, or burning sensations
* Nystagmus (uncontrolled eye movements)

Research shows gabapentin significantly improved spasticity compared to placebo, though studies haven't specifically focused on PPMS alone.

How long do side effects last?

Side effects tend to be worse when you first start taking gabapentin and often get better over time as your body adjusts. Common side effects include:

* Drowsiness or extreme sleepiness
* Vision problems (blurry or double vision)
* Dizziness
* Nausea, diarrhea, or constipation
* Memory difficulties
* Weight gain

A MyMSTeam member shared: "I was on gabapentin for about six months, but it caused greater degrees of fatigue."

If you're experiencing bothersome side effects that aren't improving, talk to your healthcare team. They can adjust your dose or explore other options to help manage your symptoms effectively.

April 6

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