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April 25
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What Is PIRA in MS? 8 Facts To Know Read Article...
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The article doesn't name a specific DMT for PIRA, but it does refer to a category called high-efficacy DMTs (HE DMTs). These are a group of more powerful disease-modifying therapies that appear to help slow the silent progression associated with PIRA.

Some well-known high-efficacy DMTs include:

- Natalizumab (Tysabri)
- O Show Full Answer

The article doesn't name a specific DMT for PIRA, but it does refer to a category called high-efficacy DMTs (HE DMTs). These are a group of more powerful disease-modifying therapies that appear to help slow the silent progression associated with PIRA.

Some well-known high-efficacy DMTs include:

- Natalizumab (Tysabri)
- Ocrelizumab (Ocrevus)
- Alemtuzumab (Lemtrada)
- Ofatumumab (Kesimpta)
- Ublituximab-xiiy (Briumvi)

Starting one of these earlier in the disease course appears to have the greatest impact on reducing PIRA and preventing long-term disability. That said, choosing the right DMT is a very personal decision. Working closely with a neurologist through shared decision-making is the best way to find a treatment that fits both health goals and personal preferences. It's always worth having an open conversation about the potential benefits and risks of any DMT.

April 25

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