Connect with others who understand.

  • Learn from expert-reviewed resources
  • Real advice from people who’ve been there
  • People who understand what you’re going through
Sign Up Log In
Powered By
Real members of MyMSTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
May 20
 · 
Reactions
A MyMSTeam Member

Ocrevus injection - Coming from someone who has no symptoms yet MRI showed different the side effects for me have been very different from what others are reporting. One dose this far and I’m feeling weakness in my legs, itching, brain fog, fatigue at times, mood swings, etc… Again my experience may be a bit different from others and I’m currently trying to figure out if I should take another dose or try something else..

June 1
A MyMSTeam Member

I haven’t tried it but was thinking about it. If it works just as well ITS BETTER THAN S 4-5 hour infusion 😜

May 20
MyMSTeam

Great question! Ocrevus Zunovo is the newer, injectable version of Ocrevus, approved in September 2024. Instead of a lengthy IV infusion at a specialized infusion center, it's a quick 10-minute injection given under the skin — twice a year, just like the original.

Here's a quick comparison to help think it through:

- Show Full Answer

Great question! Ocrevus Zunovo is the newer, injectable version of Ocrevus, approved in September 2024. Instead of a lengthy IV infusion at a specialized infusion center, it's a quick 10-minute injection given under the skin — twice a year, just like the original.

Here's a quick comparison to help think it through:

- Original Ocrevus: IV infusion, at least 2 hours per visit, requires a specialized infusion center
- Ocrevus Zunovo: 10-minute subcutaneous (under-skin) injection, given at a regular doctor's office or clinic

The good news is that clinical trials showed Ocrevus Zunovo is just as effective as the IV version, suppressing relapses and new lesions by 97% over 48 weeks. Whether it's worth switching really depends on personal circumstances. It could be a great option if:

- Long infusion appointments are difficult to manage
- There's no easy access to a specialized infusion center
- A quicker, more flexible option is preferred

Many MyMSTeam members on the original Ocrevus have mentioned planning low-energy days around infusions, partly due to pre-medication like Benadryl causing fatigue. A shorter appointment could make that easier to manage.

That said, it's always best to chat with a neurologist before making any changes to a treatment plan, as they can weigh in on what makes the most sense individually.

May 20

Related Questions

View All
A MyMSTeam Member asked a question 💭
Colville, WA

A MyMSTeam Member asked a question 💭
Chicago, IL

A MyMSTeam Member asked a question 💭
Denver, CO