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After sitting for a while, then getting up the stiffness and pain is awful!

June 24
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MyMSTeam

That stiffness and pain after sitting sounds really frustrating — you're definitely not alone in dealing with this! Many MyMSTeam members experience similar leg pain and stiffness with MS.

It's worth going back to your neurologist and being specific about how the pain affects your daily life. There are several medication Show Full Answer

That stiffness and pain after sitting sounds really frustrating — you're definitely not alone in dealing with this! Many MyMSTeam members experience similar leg pain and stiffness with MS.

It's worth going back to your neurologist and being specific about how the pain affects your daily life. There are several medication options that doctors commonly consider for MS-related leg pain and stiffness:

- Gabapentin (Neurontin) or Pregabalin (Lyrica) — often used for nerve-related pain like burning, tingling, or numbness
- Baclofen or Tizanidine — muscle relaxants that can help with stiffness and spasticity
- Over-the-counter NSAIDs like ibuprofen — can help with musculoskeletal pain, though always check with your doctor first
- Duloxetine (Cymbalta) — another option for nerve pain Beyond medication, physical therapy and regular gentle movement (like walking or yoga) have helped many MyMSTeam members manage leg pain and stiffness too.

All medications carry side effects, so it's really important to discuss the best option for your specific situation with your doctor. Don't hesitate to push the conversation further at your next appointment!

June 24
A MyMSTeam Member

Thank you! I will check it out!

June 25
A MyMSTeam Member

Magnesium glycinate helped me

June 25

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