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Real members of MyMSTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyMSTeam Member asked a question 💭
Stanton, CA90680
August 2
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A MyMSTeam Member

I know this sounds backwards from recommendations—but when I take either Vit D or Calicium supplements, I start getting leg or foot cramps, especially at night. If I don’t take supplements, or keep the dose really low (like one pill once a week), then no cramps!! I still get spasticity, but not cramps. I try to eat a good diet and get outside so that I don’t need these supplements. The last bone density scan I had was exactly the same as one I had 4 years ago.

August 2
MyMSTeam

Supplements are a popular topic in the MS community, and some people do find them helpful for managing certain symptoms like fatigue or inflammation. However, the research is mixed — studies haven't conclusively proven that supplements can reduce relapses or slow MS progression. Only FDA-approved disease-modifying therapies Show Full Answer

Supplements are a popular topic in the MS community, and some people do find them helpful for managing certain symptoms like fatigue or inflammation. However, the research is mixed — studies haven't conclusively proven that supplements can reduce relapses or slow MS progression. Only FDA-approved disease-modifying therapies (DMTs) have been proven to do that. That said, some supplements have shown promise in early research for helping with specific MS-related concerns. These include:

- Vitamin D — People with MS are more likely to have low levels, and deficiency is worth testing for
- B vitamins (B6 and B12) — Deficiencies are relatively common in MS
- Omega-3 fatty acids — May help with inflammation
- Biotin, carnitine, and coenzyme Q10 — Some studies suggest potential benefits for fatigue and cognitive function
- Melatonin and probiotics — May support sleep and overall wellness

Getting nutrients through food is generally considered safer than supplements when possible. There are also some important cautions to keep in mind:

- Supplements that boost immune response (like selenium, copper, and manganese) may worsen autoimmune activity in MS
- High doses of vitamins E and C can thin the blood
- Too much vitamin A can be toxic
- Some supplements can interact with MS medications

Always talk with your doctor before starting anything new — they can test for deficiencies and help figure out what's actually worth trying for your specific situation.

August 2

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