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has sent a letter to my gp about this as thinks the Gabapentin should be putting weight on so now have further tests also on Ocrevus every 6 months.
What do you think? Need advice please

October 1
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A MyMSTeam Member

This is quite a quandary that you have here the fact that you're on both Gabapentin and Ocrevus as I am on, you should be gaining weight, not losing weight. It might be something else there may be some other medical condition that that's going on that may be causing you to lose weight. Get checked for cancer, diabetes and other illnesses that can cause weight loss. Also look at what JJ is saying and consider Those facts also.

October 1
A MyMSTeam Member

look at the meal you put on the table for yourself.. look at the guidelines for women your age, how much they should serve and then how much fitness you need.. works for me

October 1
A MyMSTeam Member

Yes this is what some deal with or they gain weight. The medications can definitely effect your metabolism.

October 6
A MyMSTeam Member

I had an over active thyroid, which was causing dramatic weight loss, heavy sweating and axniety symptoms. I ended up needing it removed due to how ill it make me. ( this was brought on my a DMT I had called Lemtrada ) this problem only surfaced about 2 years after treatment.

Your GP will be ordering blood tests to look at quite alot of other possible factors. Do you have any other symptoms besides the weight loss?

October 2
MyMSTeam

Losing 2 stone in 2 months is significant, and it's really good that your neurologist is taking it seriously! While fitting into old clothes is a nice bonus, that amount of weight loss in such a short time does warrant investigation.

Your neurologist is right to flag this — gabapentin is actually known to cause weight *gain* Show Full Answer

Losing 2 stone in 2 months is significant, and it's really good that your neurologist is taking it seriously! While fitting into old clothes is a nice bonus, that amount of weight loss in such a short time does warrant investigation.

Your neurologist is right to flag this — gabapentin is actually known to cause weight *gain* in many people, so losing weight while on it is unexpected and worth looking into. There are several MS-related reasons why unintentional weight loss can happen, including:

- Fatigue — feeling too tired to eat or forgetting to eat regularly
- Swallowing difficulties (dysphagia) — affecting up to 45% of people with MS
- Indigestion or nausea — making eating less appealing
- Medication side effects — some MS treatments can reduce appetite

Ocrevus itself isn't strongly linked to weight loss, but it's worth mentioning any changes in appetite or digestion to your care team. The further tests your GP is running are a really sensible step. When unexplained weight loss happens, doctors typically review:

- Your current medications
- Blood tests
- Dietary habits and any changes
- A swallowing assessment if needed

In the meantime, try to keep eating regularly, and consider adding protein-rich foods or drinks like protein shakes if eating feels difficult. It's worth keeping a simple food diary to share with your GP too.

October 1

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