Natalizumab was approved in 2004 by the FDA for multiple sclerosis (MS). It was subsequently withdrawn from the market by its manufacturer after it was linked with three cases of PML. All 3 initial cases were taking natalizumab in combination with interferon beta-1a. After a safety review the drug was returned to the market in 2006 as a monotherapy for MS under a special prescription program. As of May 2011, over 130 cases of PML had been reported in MS patients, all in… read more
I'm just wondering how Tysabri is going to make me feel.I've read that some people feel great except for the last week. I hope it will give me some strength and energy.
Interesting article about Rituxan vs Gileniya for those on tysabri
I'm on Tysabri for 18 months..with JC index 3.5. Unfortunately we don't have here another second line treatment option.. What do you think ? How dangerous will be to take the risk to go on with tysabri ? Did anyone of you pass such difficult choice ?
I was just wondering if anyone has tried Tysabri Infusion, and how they are doing? I am thinking of trying it, but I am very scared. I almost died when I tried Copaxone. My white blood cells dropped to under 0.5 I have not taken anything for 3 years now, but my MS is now progressing. Especially my balance.
My partner has been offered to try natalizumab or Fingolimod due to her last prevention medicine failing its duty. The side effects described seem severe can someone who is on or has been on one of the two or both please advise me of the medicine and how it affected them, how effective the drug is to prevent relapses and lesions and how the drug can or has affected the person taking on day to day, week to week and month to month basis.
Our intent is to find… read more
I'm getting ready start this medicine as long my JCV test comes back in my favor (which it should like several months ago). I'm a bit nerves being that it's an infusion and the risk that come with it. I just want to know your experiences with this treatment. Thank you all in advance and be blessed!!
Hi everyone, Iv just got back from my neurologist and he's taken me off plegridy he has said it was a fail for me. Iv had 3 relapses since June last year.
He's suggested being put on natalizumab or fingolimod. I was just wanting to know what everyone's experiences are from being on ether of them. As he's left it up to me to decide.
Thanks in advance everyone. X
I'm on Tysabri from 18 months ..but I am JC+ with high titre: 3.5 I don't have another option from switching the treatment : only Copaxone wich is very low for my ms activity . I'm afraid of PML but also afraid of my MS. My Dr told me that I have to take the PML risk because we don't have in my country another 2nd line ms drugs ..
Did anyone of you continue with Tysabri & high JC + ?
I know Aubogio does not have the plm risk is there’s ny other ms meds that do not have pml as a risk?? I won’t know part of that!