“Lately I wake up at night with the corner of my pillow soaked because of drooling. Is this just life and getting older, or is this MS?” asked one member of MyMSTeam. MS can cause drooling if it affects the muscles in your face or makes it harder to swallow.
Aging, other health conditions, and some medications can also cause or worsen drooling.
We’ll cover ways MS can cause drooling, how this symptom affects people, and some options for how to manage it.
There are several causes of drooling in people with MS. You can work with your neurologist to pinpoint the cause in your case and find the best treatments for your needs.
Swallowing ProblemsAnything that makes it harder to swallow can result in drooling. Saliva pools in your mouth and can spill out.

Problems with swallowing are referred to as dysphagia. In MS, inflammation and damage to myelin can interfere with the muscles involved in swallowing.
Drooling and difficulty swallowing can be a dangerous combination if you breathe saliva into your airway. Breathing anything other than air into your lungs can raise your risk for aspiration pneumonia if you don’t cough it out.
People with MS are at a higher risk for developing aspiration pneumonia.
Facial WeaknessDrooling may also be caused by facial muscle weakness in people with MS. Drooling can develop when MS damages brain nerve cells (neurons) that control the muscles that move the cheeks and the lips.
Facial weakness on one side may be connected to Bell’s palsy, which occurs in 0.2 percent of people living with MS. “I suddenly find myself drooling,” said one MyMSTeam member. “I blame it on my dropped mouth, as that’s the only side that does it.”
Other Causes of DroolingAlthough nerve damage is the most frequent cause of drooling in MS, the symptom can also occur for other reasons, including other neurological disorders.
Conditions including chronic acid reflux, allergies, and Parkinson’s disease can all lead to drooling. Certain medications can also cause drooling.
Drooling can affect people with MS in different ways. For some MyMSTeam members, it occurs only at night.
One member wrote, “About a year ago, I started drooling a lot at night. It’s starting to get worse.” Another stated, “I have a lot of drooling in my sleep.”

For other people, drooling is a nonstop problem that gets in the way of socializing. “I can’t get out a full sentence without having to stop, swallow, resume,” one member said. “It’s absolutely infuriating.”
“Between confused thoughts, struggling to keep up with conversation, and then having to worry about drooling, I usually find it much easier and less frustrating to remain silent,” they continued.
Another shared, “Lately, I find myself drooling when I’m drinking, as if there’s a hole in my mouth. It’s embarrassing.”
For many people, it’s possible to manage drooling and improve quality of life with the help of your neurology team.
Quite a few treatment and management options address drooling associated with MS. You can work with your doctor or healthcare provider to find the treatment plan that best controls your symptoms without interfering with your MS care.
When Drooling Needs Immediate Medical CareStarting to drool suddenly may be a sign of a stroke, especially if it happens with other symptoms like:
If you notice drooling along with any of these signs, get emergency care as soon as possible.
Conservative MeasuresKeeping an upright posture with your head raised might help reduce excessive drooling by encouraging automatic swallowing in people with MS.
For those with nerve damage to the face, oral devices can create a better seal. You may also consider a portable suction machine to remove extra saliva.

Swallowing therapy offers another conservative option.
A speech and language pathologist can evaluate your swallowing problem. Then, they can recommend exercises to help you improve your lip seal, strengthen and coordinate your swallowing muscles, and get rid of excess saliva in your mouth.
Medication OptionsIf conservative steps don’t help, your doctor may recommend trying medication.
Injecting botulinum toxin (sold as Botox and other brand names) may help reduce saliva production and drooling. Note that botulinum toxin isn’t approved by the U.S. Food and Drug Administration (FDA) to treat drooling, and it may not be an appropriate treatment for everyone with MS.
Drugs called anticholinergics cause dry mouth and can help reduce drooling associated with MS. The most commonly prescribed medication for drooling is glycopyrrolate. Glycopyrrolate isn’t FDA-approved for drooling, either.
All medications can cause side effects. Talk treatment options over with your doctor to better understand the potential benefits and risks.
SurgeryIf drooling is severe and isn’t controlled by other measures, your doctor may mention surgery of the salivary glands. At least one study shows that drooling improved long-term after a surgical procedure.
However, this study involved adults with neurodevelopmental disabilities, rather than people living with MS. Surgery isn’t a common treatment for drooling.
On MyMSTeam, people share their experiences with multiple sclerosis, get advice, and find support from others who understand.
How has drooling related to MS symptoms affected your life? Let others know in the comments below.
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I came down with drooling only 3 years ago I was diagnosed in 2004. I found that my teeth were crumbling throughout the years but not all at once a little bit here and there maybe every 3 or 4 years… read more
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