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... According to the National Multiple Sclerosis Society, people taking the following DMTs for MS have been found to have a reduced or absent response to the COVID-19 vaccines:Gilenya (fingolimod)Mayzent (siponimod)Zeposia (ozanimod)Ponvory (ponesimod)Lemtrada (alemtuzumab) Ocrevus (ocrelizumab)Kesimpta (ofatumumab)Any biosimilars of these medications — ...

... However, the National Multiple Sclerosis Society notes that people taking the following disease-modifying therapies (DMTs) for MS may have a reduced or absent response to the COVID-19 vaccines:Gilenya (fingolimod)Mayzent (siponimod)Zeposia (ozanimod)Ponvory (ponesimod)Lemtrada (alemtuzumab)Ocrevus (ocrelizumab)Kesimpta (ofatumumab)Any biosimilars of ...

... DMTs that have been categorized as highly effective include: Alemtuzumab (Lemtrada) Natalizumab (Tysabri) Ocrelizumab (Ocrevus) Ofatumumab (Kesimpta) Ublituximab (Briumvi) Certain DMTs have been deemed “highly effective” by researchers based on their performance in clinical trials compared to other existing treatments. ...

... on the particular medication, DMTs may be given by infusions at the doctor’s office or taken at home as pills or with self-injections.Injection at HomeThe following medications can be injected subcutaneously (under the skin) at home: Glatiramer acetate (Copaxone) Interferon beta-1a (Avonex, Rebif) Interferon beta-1b (Betaseron, Extavia) Ofatumumab (Kesimpta ...

... However, the guidelines note “Some DMTs [disease-modifying therapies] used to treat MS do alter your immune system and can reduce your responses to a vaccine.”According to the National Multiple Sclerosis Society’s guidelines, individuals with MS on the following DMTs may benefit from receiving an additional dose of the vaccine: Gilenya (fingolimod) Kesimpta ...

... Diroximel fumarate (Vumerity) Fingolimod (Gilenya, Tascenso ODT) Glatiramer acetate (Copaxone, Glatopa) Interferon beta-1a (Avonex, Rebif) Interferon beta-1b (Betaseron, Extavia) Mitoxantrone Monomethyl fumarate (Bafiertam) Natalizumab (Tysabri) and its biosimilars Ocrelizumab (Ocrevus) Ocrelizumab and hyaluronidase-ocsq (Ocrevus Zunovo) Ofatumumab (Kesimpta ...

... Others block a type of lymphocyte called B cells from making antibodies (immune proteins) that damage myelin.Most experts consider highly effective DMTs for MS to include: Alemtuzumab (Lemtrada) Cladribine (Mavenclad) Natalizumab (Tysabri) Ocrelizumab (Ocrevus) Ofatumumab (Kesimpta) Rituximab (Rituxan) Ublituximab-xiiy (Briumvi) Moderate-efficacy DMTs ...

... HE DMTs include: Alemtuzumab (sold as Lemtrada) Cladribine (Mavenclad) Fingolimod (Gilenya, Tascenso ODT) Mitoxantrone (Novantrone) Natalizumab (Tysabri) and its biosimilars, such as natalizumab-sztn (Tyruko) Ocrelizumab (Ocrevus) Ofatumumab (Kesimpta) Ozanimod (Zeposia) Rituximab (Rituxan, MabThera, and Truxima) — Rituximab is not currently indicated ...

... Infused drugs must be administered by a health care provider.A few of the DMTs approved to treat MS include: Dimethyl fumarate (Tecfidera) Fingolimod (Gilenya) Glatiramer acetate (Copaxone, Glatopa) Interferon beta 1a (Avonex) Natalizumab (Tysabri) Ocrelizumab (Ocrevus) Ofatumumab (Kesimpta) If switching disease-modifying treatments is appropriate ...

... Newer treatments include: Alemtuzumab (sold as Lemtrada) Cladribine (Mavenclad) Natalizumab (Tysabri) Ocrelizumab (Ocrevus) Ocrelizumab and hyaluronidase-ocsq (Ocrevus Zunovo) Ofatumumab (Kesimpta) Ublituximab-xiiy (Briumvi) More new drugs, including new classes of drugs, are being investigated in clinical trials for their potential to prevent new lesions ...