I've been on Tysabri for more than 2 yrs now. My MRI's have remained consistent showing no new lesions where I continued to have additional lesions on Avonex... I would like to be on an oral med, but my 20 yr old daughter asked me to please stay on Tysabri as long as I can. She is scared of new side effects. I can understand her worry as she's been taking care of me since she was 16 & I was first diagnosed & divorced. ;-) I'm sure you didn't need to know all of that... Lol. Good luck to you! Stay strong!!!

I used Ty. for almost a year with no results and then developed headaches so my neuro. took me off of it and after 4 months of Rebif and steroid treatments I finally started the oral Tecfidera. No problems yet.

Hi I have been on Tysabri for 2 years. I am very happy with this med. I have tried the ABC drugs and rebif. Could not tolerate the interferon and I would still have flare ups. Tysabri has helped me. I no longer have the spasams on my left side. I still walk slow but at least I walk. Good luck to you

I'm in the same situation; I've been on Tysabri for 2 years with stable MRI's the entire time. In those 2 years I switched neuros. My old neuro (who moved away) intended to switch me to BG-12 once it was approved. My new neuro wanted me to stay on Tysabri after the 2 year mark because I am JCV negative. My MS wasn't very 'active' on MRI's before I started on Tysabri (only one new lesion in a year), but because I have a lot of lesions in my c-spine, the neuro recommended Tysabri. Basically, I've tried all injectables and had side effects with all that I didn't like. So, net net, for numerous reasons I've decided to stop Tysabri and start Tecfidera. The neuro said I can always go back on Tysabri.

Thank you I been on a year not helping