@A MyMSTeam Member - you asked about the natural route - my neurologist - after some research and the 2 of us in agreement put me in an injection for fatigue (thiamine (B1), liver extract, and my NMD added methylcobalamin (the best B12) - it was used before MS medication came out in 1991 and Dr Klenner published a paper on this treatment in the Townsend Newsletter for Doctors and Patients in Jan/Feb 2000 issue. I stumbled on this one day and took it to my neurologist - B vitamins are well known for their ability to fight fatigue - it is a compounded injection - the insurance doesn't cover it - they'd rather poison you with the prescription pad - but I can say it does work for me. I also went on the vitamin protocol for MS and my NMD tweeked the protocol - changing some brands - taking a couple out and adding in another. I take 27 pills twice a day - I hate it but it is better than the prescription poison - and I also have been on a modified Paleo diet - no gluten, red meat, dairy, legumes, no processed foods and I strictly watch the additives in my food - I do my best to use natural and organic foods - as much as that is possible - it took me almost 4 months of reading labels and trying different foods to find things I like and I can have. This long road of change has finally evened out and I lead a pretty normal existence - if there can be any normalcy to having MS. Since I quit taking tecfidera I haven't had but one occasion of having any symptoms and that episode was a mild vertigo attack I believe came from stress.
I also was tested for metal poisoning and found I have lead, mercury and gladimonium(?) the dye from MRIs poisoning. I will start my 10th and final round (I hope) of DMSA to get rid of the poisoning. I can tell the difference - getting rid of the metals poisoning has been beneficial. To each his/her own but this has worked for me - it took 4 months of intensive research - several conferences with my neurologist and I believe i am on the best road I can be on. I pray you find what is best for you - whatever that may be.

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A MyMSTea...

I also take Tecfidera. Eventhough the side effects were meant to be fierce I somehow ended up w less IBS post Tecfidera than before.

My 16 yr old grand son takes Plegrity and has since April and has no attacks since being on it. Side effects are redness in area of injection and feeling like the flu for a day but so far feels it is worth the trade off.
Between the week of Christmas 2014 and March 2015 he was only out of the hospital less than a month and since starting Pleg he has not had one issue that required meds or trip to hospital. We feel blessed. I know it is different for each person. Hope something works for you.

I am on Tecfidera and I like it. My labs looks good and my doctor, who ran a large portion of the clinical trial, gave me instructions on what to eat with the pill (specifically with breakfast) to minimize stomach and flushing side effects. I have no side effects. Pills are better than injections to me. Let me know if you have questions or what to know about the Instructions I received to take it.

I am on Tecfidera which is the latest oral that has been approved. I have had minimal side effects. Prior meds included Copaxone, Rebif and Tysabri. All were O.K. The key is to make sure that you don't get taken off one without being placed on another. I was taken off of Copaxone due to a site infection by a prior doctor who did not put me on anything else. 4 months later I had a exasperation and ended up in a nursing home for 3 months. I had full functions (walking too) prior to the incident and now I am wheelchair bound and only able to use my left arm.