Ocrevus is the only approved drug for Primary Progressive MS so if you want insurance to pay for it, and were diagnosed with PPMS, I believe you are limited to Ocrevus.

I take Ocrevus infusions every 6 months...It has been 3 1/2 yrs now without any probs!
MS Warrior x 36 years now, retired RN x 36 y ears too...😍
I am tired of self injections...Infusions are much easier to handle!!😍

Tysabri is a monthly infusion. I’ve been using it since 2009. It is not a chemotherapy like Ocrivis

Most of the new drugs, Kisempta, Ocrevus and another soon to be approved drug all work the same way, they are anti CD20 drugs. Ocrevus has the best clinical data to date, and the most. The only real difference of these drugs are how you take them. Ocrevus is an infusion every 6 months while Kesimpta is a self injection drug you take at home. I prefer Ocrevus. Another option would be Lemtrada, it has excellent evidence but there are risks and things to consider, you would really want to talk with your doctor before choosing this therapy.

Kisempta, it's a much easier to tolerate and administer once a month injection.