It seems like you meant "Aubagio." Here is detailed information about Aubagio (Teriflunomide) for Multiple Sclerosis based on the provided knowledge base:
Overview
- Aubagio is a prescription medication approved by the FDA for treating adults with relapsing forms of multiple sclerosis (MS)
- It is also known by its drug Show Full Answer
It seems like you meant "Aubagio." Here is detailed information about Aubagio (Teriflunomide) for Multiple Sclerosis based on the provided knowledge base:
Overview
- Aubagio is a prescription medication approved by the FDA for treating adults with relapsing forms of multiple sclerosis (MS).
- It is also known by its drug name, Teriflunomide.
- Aubagio has been shown to reduce rates of relapse and slow the progression of disability.
- It is not a cure for MS.
Suitability
- Not suitable for:
- People with liver problems.
- Pregnant or breastfeeding women.
- Women who have any chance of becoming pregnant.
- Men whose partners may become pregnant.
- People taking a related drug called Leflunomide.
- People with compromised immune systems, active infections, kidney or liver problems, breathing difficulties, diabetes, high blood pressure, or a history of rashes caused by other medications.
Mechanism
- Aubagio is an immunomodulatory drug.
- It works by inhibiting T and B lymphocytes (T cells and B cells), which are types of white blood cells responsible for causing the inflammatory process seen in MS.
Administration
- Form: Tablet taken orally once a day, with or without food.
- Pre-treatment tests:
- Skin-prick test for tuberculosis.
- Blood test to check liver enzymes and white blood cell levels.
- Pregnancy test for females.
Monitoring
- During treatment:
- Monthly blood tests to check liver enzyme levels and kidney function.
- Periodic checks of blood pressure and signs of infection.
Side Effects
- Common side effects:
- Diarrhea
- Nausea
- Abnormal liver test results
- Hair thinning
- Burning or prickling sensations in the skin
- Influenza
- Increased bleeding or bruising
- Rare but serious side effects:
- Liver damage
- Kidney problems
- Peripheral neuropathy (numbness or pain in hands or feet)
- Severe skin reactions
- Elevated potassium levels
- Breathing problems
Pregnancy and Birth Control
- Aubagio may cause major birth defects whether taken by either parent.
- Effective birth control should be used while taking Aubagio and for up to two years after stopping it.
- If pregnancy occurs, notify your doctor immediately for medications to reduce Aubagio levels in the body.
Results
- Clinical trials involving 2,800 people with relapsing forms of MS showed that Teriflunomide was significantly more effective than a placebo at reducing the risk of relapse, preventing new brain lesions, and slowing the progression of disabilities.
Additional Precautions
- Avoid certain vaccinations while taking Aubagio or for six months after stopping it.
- Always follow your doctor’s instructions exactly when taking Aubagio.
For more detailed information, you can visit the [Aubagio page on MyMSTeam](https://www.mymsteam.com/treatments/aubagio).
August 2, 2024