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Yes, it is possible to have MS without visible lesions initially, particularly in cases of Clinically Isolated Syndrome (CIS) or Radiologically Isolated Syndrome (RIS). In CIS, symptoms may be present with a lesion visible only in one area of the CNS, and in RIS, lesions are found incidentally without symptoms. Misdiagnosis Show Full Answer

Yes, it is possible to have MS without visible lesions initially, particularly in cases of Clinically Isolated Syndrome (CIS) or Radiologically Isolated Syndrome (RIS). In CIS, symptoms may be present with a lesion visible only in one area of the CNS, and in RIS, lesions are found incidentally without symptoms. Misdiagnosis can occur since MS symptoms can overlap with other conditions, making it crucial for neurologists to conduct comprehensive tests and rule out other diseases before confirming an MS diagnosis.

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