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Real members of MyMSTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Hey guys is this normal??

A MyMSTeam Member asked a question 💭
Lincolnton, NC

I have taken Kesimpta since last August and have never had a reaction like this. I want to know if I should be concerned about this? I currently have a enlarged lymph node on the right side of my groin, I’m not sure if it’s connected or not, but I get surgery on Wednesday (10/09) to remove it. Took my Kesimpta like normal in my thigh and this happened throughout the day but swelling started immediately after. Thanks for hearing me out and thank you for any insight.

October 2, 2024
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Reactions
A MyMSTeam Member

Ouch!

October 2, 2024
A MyMSTeam Member

Kesimpta side effects
Kesimpta may cause serious side effects, including:

See Important information

Injection-related reactions. Injection-related reactions is a common side effect of Kesimpta. Injecting this medicine can cause injection-related reactions that can happen within 24 hours (1 day) following the first injections and with later injections. Talk with your healthcare provider if you have any of these signs and symptoms:
at or near the injection site: redness of the skin, swelling, itching and pain or
that may happen when certain substances are released in your body: fever, headache, pain in the muscles, chills, and tiredness.

October 2, 2024
A MyMSTeam Member

Thank you! The lymph node is an unexplained mystery but it’s been present since May, just grown more painful. But I’ll be hopeful 🤝

October 2, 2024
MyMSTeam

Swollen lymph nodes are not a direct symptom of multiple sclerosis (MS). However, people with MS, like the general population, may experience swollen lymph nodes due to common causes like viral or bacterial infections. Some MS medications, including disease-modifying therapies, can increase the risk of infections, which Show Full Answer

Swollen lymph nodes are not a direct symptom of multiple sclerosis (MS). However, people with MS, like the general population, may experience swollen lymph nodes due to common causes like viral or bacterial infections. Some MS medications, including disease-modifying therapies, can increase the risk of infections, which might lead to swollen lymph nodes.

Here are some key points to consider:

- Swollen Lymph Nodes and MS: Swollen lymph nodes are not directly caused by MS but can occur due to infections or other conditions.
- MS Medications: Some MS medications, such as those used for relapsing-remitting MS, can increase the risk of infections, potentially leading to swollen lymph nodes. These medications include:
- Fingolimod (Gilenya)
- Siponimod (Mayzent)
- Cladribine (Mavenclad)
- Ocrelizumab (Ocrevus)
- Natalizumab (Tysabri)
- Alemtuzumab (Campath)

- When to See a Doctor: It's important to consult a doctor if swollen lymph nodes:
- Continue to get bigger
- Are present for two to four weeks or longer
- Appeared for no clear reason
- Feel very hard and do not move when you push on them
- Come with other symptoms like a high fever, sore throat, unexplained weight loss, or night sweats
- Cause difficulty swallowing or breathing

Given that you have an enlarged lymph node and are scheduled for surgery, it is crucial to discuss your symptoms and concerns with your healthcare provider. They can provide personalized advice and ensure that your treatment plan is appropriate.

Your surgery is scheduled for Wednesday, October 9th, 2024, so make sure to communicate any new or worsening symptoms to your medical team before then.

October 2, 2024

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