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What changes can you expect when transitioning from RRMS to SPMS?

It's completely understandable to feel scared about this transition after living with MS for 28 years. The shift to SPMS does bring changes, but knowing what to expect can help you prepare.

The main difference is that SPMS involves a gradual worsening of Show Full Answer

What changes can you expect when transitioning from RRMS to SPMS?

It's completely understandable to feel scared about this transition after living with MS for 28 years. The shift to SPMS does bring changes, but knowing what to expect can help you prepare.

The main difference is that SPMS involves a gradual worsening of symptoms over time, rather than the relapse-and-remission pattern you've experienced with RRMS. Interestingly, you'll likely have fewer relapses or they may stop entirely, though symptoms will continue to progress.

Common symptoms that may worsen or develop include:

- Walking difficulties and balance problems (affecting more than 88% of people with SPMS)
- Increased fatigue
- Muscle stiffness and spasms
- Cognitive changes like memory or word-finding difficulties
- Bladder and bowel issues
- Vision problems
- Numbness or tingling

However, it's important to know that over two-thirds of people with SPMS retain their ability to walk, though many use assistance devices like canes or walkers. Each person's experience is unique, and disability levels vary significantly. There are treatment options available for SPMS. Several disease-modifying therapies are FDA-approved for active SPMS, including Mayzent, Zeposia, Mavenclad, and others. These medications can help slow progression and reduce the risk of worsening disability.

Talk with your neurologist about which treatments might be right for you and what lifestyle modifications could help manage your symptoms. You're not alone in this transition—a MyMSTeam member shared, "I feel I am doing well for coming up on 19 years with MS," even while managing balance issues with a walker.

 AI-generated responses are not a substitute for medical advice. These services are not intended to diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.

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