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Real members of MyMSTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
May 30
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A MyMSTeam Member

I take Dalfampridine (Ampyra) twice daily (7 am & 7 pm) and for me it has been very helpful, along with PT, at getting me back in balance. I will add on one observation: I noted something that I had actually traced too. This medication, since it tied back to periods when was taking it and was out of the medication and hence did not take it, I asked my neurologist look back at the data available to research whether or not this was a known side effect or not. Looking all the way back to its initial trials she found nothing of the sort reported, but my own experience is that the medication actually increases my dream activity. Not in terms of movement and the like, but rather in terms of how vivid my dreams are and how often I will now remember them for a bit after I wake up. Not something to be taken as a negative response, because I have some memory of dreaming before I was diagnosed, just my observation that Dalfampridine is reactivating some part of my brain too, which is why I call them "Dalfampridine Dreams". Considering how many things Ms has taken away from our minds, this could be a positive. πŸ™‚

June 1
A MyMSTeam Member

Anytime that's what team members are for man. I know where your coming from on the falls, they sure bite - kick in the pants bring you down. I hate that you have fell 3 times as well. I have badly Deteriorated disc in my back and my Spine has lesson almost losson half size. Do you have badly Deteriorated disc as well? Just wondering

May 30
A MyMSTeam Member

Thanks for your shared experience. Sorry for your falls.

May 30
MyMSTeam

That's a really important observation β€” noticing a pattern like that after starting a new medication is worth paying attention to!

Dalfampridine (Ampyra) is an FDA-approved oral medication designed to help improve walking in people with MS by supporting nerve signal conduction in damaged myelin. It can be helpful for many Show Full Answer

That's a really important observation β€” noticing a pattern like that after starting a new medication is worth paying attention to!

Dalfampridine (Ampyra) is an FDA-approved oral medication designed to help improve walking in people with MS by supporting nerve signal conduction in damaged myelin. It can be helpful for many people, but it's not without considerations.

Falls in MS can be linked to several factors, including:

- Poor balance
- Dizziness
- Slow walking speed
- Fatigue
- Side effects from medications

It's hard to say definitively whether Dalfampridine is contributing to the falls without talking to your neurologist. However, three falls since starting it is something your care team should absolutely know about. In the meantime, some practical steps that may help reduce fall risk include:

- Using a mobility aid like a cane or walker for extra stability
- Removing trip hazards at home (loose rugs, cords, etc.)
- Installing grab bars in key areas
- Working with a physical therapist on balance and core strength exercises
- Being extra cautious during symptom flare-ups

Please bring up the falls with your neurologist soon β€” they can assess whether Dalfampridine is the right fit for you or if adjustments are needed.

May 30
A MyMSTeam Member

Currently I'm still taking it...

June 2

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