Rituximab (Rituxan) is sometimes used off-label to treat MS. While it's generally considered effective, it does come with some potential side effects worth knowing about.
Some notable side effects include:
- Infusion reactions — chills, fever, or headache during or after the infusion
- Infections — including respiratory Show Full Answer
Rituximab (Rituxan) is sometimes used off-label to treat MS. While it's generally considered effective, it does come with some potential side effects worth knowing about.
Some notable side effects include:
- Infusion reactions — chills, fever, or headache during or after the infusion
- Infections — including respiratory infections, which are among the most commonly reported
- Tendon damage — this is rare, but has been associated with rituximab use
- The "crap gap" — some people notice a return of fatigue or MS-like symptoms as the medication starts to wear off before the next infusion
A MyMSTeam member shared: "Does anyone who takes rituximab notice anything different when it's time for another infusion? I am due for my second infusion in four weeks. The first was six months ago. I'm feeling extremely drained and like I'm getting a cold."
It's always a good idea to talk to your neurologist if you notice any unexpected symptoms, especially signs of infection like fever, shortness of breath, or a full-body rash. Never stop taking a DMT without consulting your doctor first.
June 12