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FDA OKs first human trial testing oral MS remyelination therapy
FDA OKs first human trial testing oral MS remyelination therapy
June 26
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Answer Summary

Members shared excitement about a remyelination therapy trial aimed at restoring lost function in multiple sclerosis, with many expressing... Read more

Members shared excitement about a remyelination therapy trial aimed at restoring lost function in multiple sclerosis, with many expressing hope that it could one day repair myelin rather than just slow progression. Several members described their personal approaches, including waiting for full FDA approval, consulting their neurologists, or actively reaching out to MS specialty centers to learn about participating in the trial. A recurring theme was cautious optimism mixed with urgency, as many shared that worsening disability has them open to exploring any promising option that could help.

A MyMSTeam Member

With any new drug, I usually will wait until it has been released and used for a couple of years. Call me paranoid, however I don’t trust the FÐA especially after the c0vid debacle.

June 26
A MyMSTeam Member

I left a message with my Ms dr's assistant yesterday, asking about being involved in this trial 🙏🏼

September 29
A MyMSTeam Member

There are a couple going on the newest being PTD802. The FDA cleared the investigational new drug application in June 2026 allowing clinical trials to begin. It's a selective GPR17 antagonist. In MS GPR17 expression gets dysregulated which stops OPC's from maturing into myelin-producing cells. PTD802 blocks this receptor to remove the blockade and promote remyelination. I'm cautiously optimistic

June 27
A MyMSTeam Member

That's super exciting. I would totally try it. I was recently approved to go to the multiple schlorosis center of excellence in okc. I'm definitely going to ask about it or anything that actually repairs myelin rather than just slows progression. I'm game to be a lab rat for whatever could help me and others.
I got a referral to a nuerology center too. Thank you Jesus 🙏

https://omrf.org/patients/multiple-sclerosis-ce...

https://neurologycare.com/?gad_source=1&gad...

Neurology Care
Neurology Care
Multiple Sclerosis Center of Excellence
Multiple Sclerosis Center of Excellence
June 26
A MyMSTeam Member

It’s in phase two- safety and ethics, I am going to wait until it has fda clearance

June 26

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