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FDA OKs first human trial testing oral MS remyelination therapy
FDA OKs first human trial testing oral MS remyelination therapy
June 26
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Answer Summary

Members responded with hope and cautious optimism to the question about an FDA-cleared remyelination therapy trial for multiple sclerosis,... Read more

Members responded with hope and cautious optimism to the question about an FDA-cleared remyelination therapy trial for multiple sclerosis, with many expressing strong interest in treatments that could restore function rather than just slow progression. Several members shared that they plan to ask their neurologists about the trial, with one member providing details about PTD802, a drug that targets a receptor blocking myelin-producing cells. A recurring theme was the balance between excitement and patience, as many members said they would wait to see safety data and FDA approval before trying anything new.

A MyMSTeam Member

With any new drug, I usually will wait until it has been released and used for a couple of years. Call me paranoid, however I don’t trust the FÐA especially after the c0vid debacle.

June 26
A MyMSTeam Member

There are a couple going on the newest being PTD802. The FDA cleared the investigational new drug application in June 2026 allowing clinical trials to begin. It's a selective GPR17 antagonist. In MS GPR17 expression gets dysregulated which stops OPC's from maturing into myelin-producing cells. PTD802 blocks this receptor to remove the blockade and promote remyelination. I'm cautiously optimistic

June 27
A MyMSTeam Member

That's super exciting. I would totally try it. I was recently approved to go to the multiple schlorosis center of excellence in okc. I'm definitely going to ask about it or anything that actually repairs myelin rather than just slows progression. I'm game to be a lab rat for whatever could help me and others.
I got a referral to a nuerology center too. Thank you Jesus 🙏

https://omrf.org/patients/multiple-sclerosis-ce...

https://neurologycare.com/?gad_source=1&gad...

Neurology Care
Neurology Care
Multiple Sclerosis Center of Excellence
Multiple Sclerosis Center of Excellence
June 26
A MyMSTeam Member

It’s in phase two- safety and ethics, I am going to wait until it has fda clearance

June 26
A MyMSTeam Member

I really hope it is successful 🙏

June 26

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