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I’m on my second treatment. I had to have the infusions two weeks apart for my first time. I’ve been nothing but tired constantly. Has this happened to anyone else? I know I just recently lost my husband and I’ve been remodeling my home, and I had a massive flood. I feel like my legs are worse. My head is worse. Any suggestions?

July 31
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A MyMSTeam Member

I am so sorry for your loss🙏 . The loss of a loved one ,especially a spouse is so heartbreaking. I could only imagine how the grief , plus the stress from your home is causing your body to react that way. What does your neurologist suggest ? I can only suggest trying to give your self time to rest , and to heal during this difficult time.

July 31
A MyMSTeam Member

Yes! Between November 2015 and March 2016 i lost my husband to lung cancer, i was diagnosed with MS AND breast cancer, (surgery, radiation and chemo followed) all while working full time. I don’t know how i got thru it. I have wonderful co-workers.

July 31
MyMSTeam

First, so sorry for the loss of your husband. Carrying grief while managing MS and everything else you're dealing with — a remodel AND a flood — is an enormous amount for anyone. It makes complete sense that your body is struggling right now.

Stress is a well-known trigger for MS symptoms worsening, and what you're Show Full Answer

First, so sorry for the loss of your husband. Carrying grief while managing MS and everything else you're dealing with — a remodel AND a flood — is an enormous amount for anyone. It makes complete sense that your body is struggling right now.

Stress is a well-known trigger for MS symptoms worsening, and what you're describing — increased fatigue, leg weakness, and cognitive fog — are all recognized signs that a flare may be happening. It's also worth knowing that sometimes symptoms worsen temporarily without it being a true relapse. These are called pseudoexacerbations, and they can be triggered by emotional stress, physical exhaustion, or other external pressures — all of which you're experiencing right now.

A true flare typically involves:
- New or worsening symptoms lasting at least 24–48 hours
- No other obvious cause like infection or fever
- Occurring at least 30 days after a previous flare Some MyMSTeam members have described similar experiences where overwhelming life events seemed to coincide with symptom flares, feeling like their body was reflecting everything their mind was going through.

The most important step right now is to contact your neurologist and describe what you're experiencing. They can help determine whether this is a true relapse, a pseudoexacerbation, or a wearing-off effect between infusions — and adjust your care plan if needed.

July 31

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