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Real members of MyMSTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
15 hours ago
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Switching From One MS Treatment to Another: 5 Must-Knows Read Article...
A MyMSTeam Member

I liked taking a pill but I had to get off of it because my immune system lowed so much that I always would get oral thrush

6 hours ago
MyMSTeam

It sounds like you might be referring to Siponimod (Mayzent) — an FDA-approved oral medication used to treat relapsing forms of MS, including active secondary progressive MS (SPMS).

It works by attaching to specific receptors on immune cells, keeping them in the lymph nodes and away from the brain and spinal cord. This may Show Full Answer

It sounds like you might be referring to Siponimod (Mayzent) — an FDA-approved oral medication used to treat relapsing forms of MS, including active secondary progressive MS (SPMS).

It works by attaching to specific receptors on immune cells, keeping them in the lymph nodes and away from the brain and spinal cord. This may help slow MS progression and reduce relapses. Based on feedback from MyMSTeam members, here are some key points about Siponimod:

Benefits:
- Once-daily oral pill — easy to take
- Starter-pack titration to ease you into treatment
- Patient assistance programs available to help with costs

Things to be aware of:
- Can cause headaches, dizziness, and elevated blood pressure
- May cause swelling in hands, ankles, or face
- Increases infection risk and requires regular monitoring of white blood cell counts

A major clinical study found it reduced the risk of confirmed disability progression by 21% compared to a placebo, which is meaningful for people with active SPMS.

As always, a neurologist is the best person to help decide if this is the right fit. It's worth having that conversation!

15 hours ago

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