Great question! Here's a summary of what MyMSTeam members and clinical studies have shared about body changes — both positive and not-so-great — while on Ocrevus.
The Good
Many people have noticed meaningful improvements over time, including:
- Better walking ability
- More energy
- Improved balance
- Reduced brain fog
- Fewer Show Full Answer
Great question! Here's a summary of what MyMSTeam members and clinical studies have shared about body changes — both positive and not-so-great — while on Ocrevus.
The Good
Many people have noticed meaningful improvements over time, including:
- Better walking ability
- More energy
- Improved balance
- Reduced brain fog
- Fewer relapses (studies show up to 46–47% reduction in yearly relapse rates)
- Slowed disability progression (up to 40% risk reduction in studies)
- Reduced new brain lesions on MRI (77–83% reduction) The Not-So-Great
Some common side effects people experience include:
- Fatigue and headaches after infusion day
- Infusion reactions (itching, flushing, throat symptoms, blood pressure changes)
- Upper respiratory infections like colds or sinus infections
- Skin infections
- Bronchitis
One MyMSTeam member shared: after their first infusion, they had a headache, felt light-headed, and experienced extreme fatigue for several days before things improved. Serious changes to watch for
These are less common but important to know about:
- Serious infections (including herpes or hepatitis B reactivation)
- Lower antibody levels, raising infection risk
- A rare but serious brain infection called PML
- Liver injury
- Increased cancer risk, including breast cancer
Always contact your doctor right away if something feels off. It's worth keeping a log of how you feel after each infusion to share with your care team.
AI-generated responses are not a substitute for medical advice. These services are not intended to
diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.
October 14
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