MyMSTeam

Yes, mood swings and cognitive changes like incoherency are very much a recognized part of living with PPMS. You're definitely not alone in experiencing this — as one MyMSTeam member put it, their mood can be "up and down like a yo-yo."

Here's why this happens with PPMS:

- PPMS can cause lesions in areas of the brain that Show Full Answer

Yes, mood swings and cognitive changes like incoherency are very much a recognized part of living with PPMS. You're definitely not alone in experiencing this — as one MyMSTeam member put it, their mood can be "up and down like a yo-yo."

Here's why this happens with PPMS:

- PPMS can cause lesions in areas of the brain that regulate emotions, leading to rapid, unpredictable mood changes
- Cognitive challenges like brain fog, difficulty concentrating, and unclear thinking are common PPMS symptoms
- The stress and grief of living with a progressive condition can intensify mood swings further Rapid, minute-by-minute mood shifts can also be linked to a condition called pseudobulbar affect (PBA), which can occur in MS. This involves sudden, uncontrollable emotional episodes that feel out of proportion to the situation.

It's really important to talk to your neurologist about the severity and frequency of these mood swings, as there are strategies and treatments that can help, including therapy and medication adjustments.

Given that UTIs, sepsis, and dehydration are also part of your picture, these can significantly worsen cognitive symptoms and mood — so keeping your care team closely informed about all of these together is especially important.

 AI-generated responses are not a substitute for medical advice. These services are not intended to diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.

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