murphy... I feel sometimes that tysabri made me worse.. my neuro doesn't agree with me.. she says tysabri is good for me and that my symptoms are all in my head and not ms related symptoms.. having hard time believing her. I feel sometimes we have to be our own doctor.

Neuro replied to my email... she said; im sorry to hear this and im concerned if you stop you will have significant relapse again, will you consider stopping 2 months and try again or new treatment. Its so hard to make up my mind especially when you sense fear in family and doctor. I feel like screaming :O

I didn't have any problems when I stopped, after almost 3 years on Tysabri. Honestly, I didn't even know it was a problem to stop it. Now I'm retroactively worried.

I'm on Tysabri; just had my 10th Infussion. Planing to get off treatment cause I feel headaches, sleepless nights, muscle spasms are the cause of it.

I was on Tysabri for 7 years. It worked well but I'm JC positive and decided it was not a long term solution. So, I'm now on Rituxan. My neurologist didn't have me do a "flush" but I didn't over lap either. I started the rituxan the day I would have gotten my next Tysabri treatment. I'm convinced that is why I didn't have a rebound effect.