You still have more options. Three orals: Aubagio, Gilenya and Tecfidera. 2 more interferons: Rebif and Extavia (same as Betaseron)

I switched to rituxan. It's not FDA approved for MS so you may have to jump through hoops to get it but it's been well received. My Neurologist said the company holding the patent will be losing it soon so they never finished the testing to get it approved. No money in it. Darn pharmaceutical companies.

I've taken Novantrone in the past which helped a great deal, however I've taken the lifetime limit.