*AST and ALT...typo

As you have both established by looking it up, yes! Gilenya CAN cause an increase in liver enzymes and have an effect on liver function. The manufacturer recommends having a baseline liver function test done (before starting the drug, check AST and AKT to see where you started). Then they recommend checking them every 3 months while on Gilenya. Also, watching for any sugns of liver dysfunction, as was mentioned above (nausea, stomach pain, yellowing of skin or whites of eyes, dark urine, etc). As long as you are being monitored and have a normal baseline liver function, it should not be an issue.

Thanks Mary.

My answer to my question according to the gelenya site - is:
This medication may rarely cause serious liver problems. Tell your doctor right away if you experience: yellowing eyes/skin, dark urine, stomach/abdominal pain, persistent nausea.

@A MyMSTeam Member the link below does show that there are some information regarding the effects on the liver. Check the link below, it is the Gilenya web site.

http://www.gilenya.com/index.jsp?site=PS015657

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