Cymbalta (Duloxetine) for Multiple Sclerosis | MyMSTeam

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Cymbalta is a prescription drug approved by the U.S. Food and Drug Administration (FDA) to treat depression, anxiety, diabetic peripheral neuropathy, fibromyalgia, and chronic musculoskeletal pain. Cymbalta is sometimes prescribed to treat depression associated with multiple sclerosis (MS). Cymbalta is also known by its drug name, duloxetine.

Cymbalta is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. Cymbalta is believed to work by changing the balance of neurotransmitters in the brain.

How do I take it?
Cymbalta is taken once or twice daily.

Cymbalta comes in delayed-release capsule form.

Side effects
The FDA-approved label for Cymbalta lists common side effects including nausea, dry mouth, drowsiness, constipation, decreased appetite, and excessive sweating.

Rare but serious side effects listed for Cymbalta include worsening depression and suicidal thoughts, liver toxicity, low or high blood pressure, serotonin syndrome, abnormal bleeding, severe skin reactions, mania, seizures, glaucoma, and urinary retention.

For more details about this treatment, visit:

Cymbalta — RxList

Depression Treatment — National MS Society

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