On tecfidera, started yr ago when diagnosed, symptoms have worsened over year, just released from hospital yesterday for relapse. Does this indicate the ms med not working? Moved to TX just under year ago, on my second Neuro, and based on this relapse, already have referral now to ms clinic hour away, the reg doc at hospital stressed me to travel farther for care. But today starts the stress, have not been at job long enough for FMLA. They are really understanding, but how do you explain, it… read more
Published on Apr 23, 2018
Disease modifying therapies (DMTs) – the front line in our fight against MS.
Some data presented👇 by percentage:
@ Avonex decreases relapses by 30% and has no effect on brain atrophy.
@ Copaxone
Decreases relapse rates by 30%
Decreases brain atrophy by 20%
@ Aubagio Tablet
Decreases relapse rates by 30%
Decreases brain atrophy by 20%
@Gelenya
Decreases relapse rates by 60%
Decreases MRI activity by 60 to 70%
Decreases brain atrophy by 34%
Chance to improve symptoms is moderately high.
@ Tysabri:
Decreases relapse rates by 67%
Decreases MRI activity by 80%
Decreases brain atrophy by 45%
do not use this medication if you are JCV positive.
@ Tecfidera. Tablets
Decreases relapse rates by 50%
Decreases MRI activity by 50%
Decreases brain atrophy by 30% @ Rebif is Interferon beta 1a, which is also sold under the brand name of Avonex. Avonex is a slightly different formulation.
@ Ocrevus
decreases relapse rates by 80%
decreases MRI activity by 95%
decreases brain atrophy by 45%
Chance of improving symptoms is very high in RRMS.
Decreasing relapse rates should be a must when fighting MS because a relapse can be unexpectedly horrific.
Prayers for you may need to get on disability and yes it sucks but sometimes you're not going to be able to work sorry I know how you feel keep taking care of yourself
MSF 30 Deciding if Ocrevus Is Right for You.
I hope this helps
The caution about Ocrevus is that “the risks may outweigh the rewards.” The main determining factor is age.
Ocrevus has been shown to work best when lesions are active and enhanced, most likely at the time of diagnosis. Because PPMS already weakens the immune system, and because Ocrevus depletes certain B-cells, so it could further compromise the immune system. That could leave you vulnerable to dangerous infections.
@ Ocrevus
decreases relapse rates by 80%
decreases MRI activity by 95%
decreases brain atrophy by 45%
Chance of improving symptoms is very high in RRMS.
Decreasing relapse rates should be a must when fighting MS because a relapse can be unexpectedly horrific.
and
MSF 262 SSDI MS Disability. I hope this helps.
If you live with multiple sclerosis and are unable to work due to an MS-related disability and/or other conditions, you might be entitled to Social Security Disability Insurance (SSDI) or Supplemental Security Income
(SSI) benefits. The Social Security Disability Guidebook can assist you in deciding whether applying for disability benefits is right for you, and in navigating the complex application process. Additionally, information about certain types of MS that may qualify a person for an expedited review of their application for disability benefits is provided on this website in the section on Compassionate Allowances. The Social Security Administration (SSA) recognizes MS as a chronic illness or impairment that can cause disability severe enough to prevent an individual from working. If you have any of the following symptoms, or any combination of these or other symptoms that prevent you from working, you might qualify for Social Security benefits:
Difficulty with walking and other motor skills Difficulty seeing
Difficulty concentrating or completing simple tasks
Difficulty remembering
Extreme fatigue, regardless of sleep
Speech impairment
Side effects of medication(s)
While SSI and SSDI provide different benefits, SSA uses the same disability determination process for both. You can even qualify for both at the same time. This Guidebook, Applying for Social Security Benefits: A Guidebook for People with MS and Their Healthcare Providers focuses primarily on the SSDI application process but includes helpful information for both programs. If you need additional information or help as you read through the Guidebook, contact an MS Navigator, call SSA at (Phone number can only be seen by the question and answer creators).
The Society's MS Navigators help identify solutions and provide access to the resources you are looking for. Call (Phone number can only be seen by the question and answer creators) or see "More info" to contact us online.
MSF 288 Comparison of MS Disease-Modifying Therapies Overview
I hope this helps.
Multiple Sclerosis Center 1600 East Jefferson St., Suite A Seattle, WA 98122
T (Phone number can only be seen by the question and answer creators) F (Phone number can only be seen by the question and answer creators)
www.swedish.org/ms or www.swedishmscenter.org
There are now 15 medications that are approved by the US Food and Drug Administration (FDA) to treat MS. These are often called Disease Modifying Therapies (DMTs) or Disease Modifying Drugs (DMDs) because they modify the progression of MS. All of these medications have been shown to slow the course of MS in multiple well-designed research studies. These medications are (in alphabetical order): Alemtuzumab (Lemtrada) Daclizumab (Zinbryta) Dimethyl fumarate (Tecficera) Fingolimod (Gilenya) Glatiramer acetate (Copaxone, Glatopa) Interferons Interferon beta-1a (Avonex, Plegridy, Rebif) Interferon beta-1b (Betaseron, Extavia) Mitoxantrone (Novantrone) Natalizumab (Tysabri) Ocrelizumab (Ocrevus) Teriflunomide (Aubagio)
What do DMTs do? These medications slow the course of MS. Patients taking DMTs have fewer attacks, milder disease courses and less disability. These medicines are not expected to reverse nervous system damage that was done in the past, but rather lessen the chance of damage occurring in the future. While people are taking the medications, the course of the disease is slowed, but if the medications are discontinued the MS reverts to its previous course.
Which DMT is the best? Our Center does not believe that any one of these medications is “the best”. Similarly, there is no consensus within the medical field about which medication is best. Rather, each medication has advantages and disadvantages that must be weighed for each patient. Which DMTs is most medically effective is not known.
But I have read that one of the DMTs is the best one. The only way to determine which medication works the best is to do a head-to-head study of one medication versus another. These types of studies are needed to determine the effectiveness and side effects of the DMTs compared to each other. Very few of these studies have been done. More information on head-to head studies of DMTs is available on our website.
Thanks!!!