Has anyone been put on Kesimpta for PPMS, and concerns about hair loss and cavities?
Currently, Kesimpta (ofatumumab) isn't typically used for PPMS. The only FDA-approved medication specifically for PPMS is ocrelizumab (Ocrevus), which is given as an infusion. Ocrelizumab works by reducing B cells that contribute to Show Full Answer
Has anyone been put on Kesimpta for PPMS, and concerns about hair loss and cavities?
Currently, Kesimpta (ofatumumab) isn't typically used for PPMS. The only FDA-approved medication specifically for PPMS is ocrelizumab (Ocrevus), which is given as an infusion. Ocrelizumab works by reducing B cells that contribute to disease progression and has been shown to slow disability in people with PPMS.
For your concerning symptoms of significant hair loss and dental issues, these need immediate attention from your healthcare team. While these symptoms can sometimes occur with MS or as side effects of certain medications, they could also indicate other health issues that need evaluation.
It's important to discuss with your neurologist:
- Whether your current treatment plan is working effectively for your PPMS
- The cause of your hair loss and dental problems
- Whether these symptoms could be related to your MS, medications, or other factors
Your doctor can help determine the best treatment approach for your PPMS and address these troubling symptoms you're experiencing.
November 26, 2025
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